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Naturally occurring variation in GLP1R cannot replicate that level of activation, which is why we don't see GLP1R variants with dramatic effects on BMI
This hormone influences how the body processes and stores nutrients, particularly fat
Open Immunol
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For GLP-1R and GCGR, CHO-K1 cells (30,000 cells/well) were seeded into Isoplate-96 plates and incubated for 24 h at 37 C in 5% CO 2
Trials have shown compelling weight loss, robust reductions in triglycerides, LDL cholesterol, liver fat content, & blood pressure
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